CMDA's The Point

Adult Stem Cells Are the Gold Standard

March 28, 2019
Oil Bubbles July 31, 2018

by David Prentice, PhD

Adult stem cells are the successful gold standard of stem cells, especially when it comes to patients and therapies. Adult stem cells are in fact the only type of stem cell to have shown validated, published results of therapeutic benefit to patients. A recent published review of stem cell research documents the significant efficacy gap between embryonic and adult stem cells.

Embryonic stem cells require the destruction of a young human being. Despite the claims made for two decades of their almost mythical potential to cure all known maladies, not a single cure has come from embryonic stem cells. Embryonic stem cell studies have been touted as “important life-saving research” even by the current National Institutes of Health (NIH) Director, yet no lives have been saved by embryonic stem cells. Questions remain about their efficacy as well as the ability to measure effects due to embryonic stem cells as opposed to placebo effect or normal tissue regeneration. There are significant concerns for tissue destruction or tumorigenesis due to embryonic stem cells, since their inherent cellular characteristic is rapid proliferation as well as accumulation of mutations.

Embryonic stem cells are more akin to cancerous cells than to regenerative cells. But their most egregious failing comes from the fact that young human lives are sacrificed to derive embryonic stem cells. The research fails due to the moral problem of treating nascent human beings as property, as expendable raw materials. The U.S. government is supposed to conduct responsible, scientifically worthy human stem cell research, but embryonic stem cell research is neither responsible nor scientifically worthy because it demonstrably wastes taxpayer dollars as well as the lives of some of our youngest human beings. The false promises made to patients about potential embryonic stem cell cures only compound the unethical nature of this research. The NIH registry of human embryonic stem cell lines, a listing created by destroying young human beings, has created a government-encouraged cottage industry for further human embryo destruction to qualify for federal taxpayer dollars; the names and numbers in the registry sit as memorial markers of the lives sacrificed for science. The registry should be closed and the funds reallocated to patient-centered adult stem cell research.

Adult stem cell research, in contrast, is life-affirming research. Adult stem cells put the patient first, without requiring the destruction of the stem cell donor (who is often the patient). Besides trumping embryonic stem cells on the ethical front, adult stem cells are vastly superior in their practical advantages. Their actual benefits for patients long ago left embryonic stem cells disappearing in the rearview mirror, with the number of patients treated around the globe now approaching an estimated two million, including children in the womb. Numerous applications are close to or already in the clinic, including many currently in clinical trials as well as some therapies approved through all phases of FDA testing. Peer-reviewed, published, successful results abound, with hundreds of papers now documenting therapeutic benefit of adult stem cells in clinical trials and progress toward fully tested and approved treatments.

But the numbers and scientific papers have a more important, very human side. View this video as a starting point, learn more about the people and the lifesaving science of adult stem cells, and share this information. Patients as well as physicians need to know about these growing opportunities and be steered toward valid, safe treatments and trials. Policymakers need to see the true impact of supporting adult stem cells.

Adult stem cells are demonstrably the gold standard of stem cells. The results highlight how an ethical system that values all human life provides advantages to science and medicine. That’s a winning theme for patients, healthcare professionals and society.

David Prentice, PhD

About David Prentice, PhD

David A. Prentice is Vice President and Research Director for the Charlotte Lozier Institute. He is also Adjunct Professor of Molecular Genetics at the John Paul II Institute, The Catholic University of America and was a Founding Advisory Board Member for the Midwest Stem Cell Therapy Center, a unique comprehensive stem cell center in Kansas that he was instrumental in creating. In 2020, he was appointed by the Secretary of HHS to the federal Human Fetal Tissue Ethics Advisory Board. Dr. Prentice has over 40 years’ experience as a scientific researcher and professor, including previous service as senior fellow for life sciences at the Family Research Council, Professor of Life Sciences at Indiana State University, and Adjunct Professor of Medical and Molecular Genetics, Indiana University School of Medicine. He established Stem Cell Research Facts, an educational website providing scientific facts and patient-centered videos about adult stem cells, and is a founding member of Do No Harm: The Coalition of Americans for Research Ethics, and an advisory board member for the Center for Bioethics and Human Dignity. He has provided scientific advice for numerous medical professionals, legislators, policymakers and organizations at the state, federal, and international levels. Dr. Prentice received his Ph.D. in biochemistry from the University of Kansas, and was at Los Alamos National Laboratory and the University of Texas Medical School-Houston before joining Indiana State University where in addition to his research and teaching, he served as Acting Associate Dean of Arts and Sciences and Assistant Chair of Life Sciences. He was recognized with the University’s Caleb Mills Distinguished Teaching Award and Faculty Distinguished Service Award. He has taught courses ranging from non-majors biology to advanced and graduate courses including developmental biology, embryology, cell and tissue culture, history of biology, science and politics, pathophysiology, medical genetics, and medical biochemistry. Several of his courses were also taught on-line. He received the 2007 Walter C. Randall Award in Biomedical Ethics from the American Physiological Society, given for promoting the honor and integrity of biomedical science through example and mentoring in the classroom and laboratory. Dr. Prentice’s research interests encompass various aspects of cell growth control, cell and developmental biology; one major focus is adult stem cells. He has reviewed for various professional publications including The Journal of the American Medical Association. He is an internationally-recognized expert on stem cell research, cell biology and bioethics, and has provided scientific lectures and policy briefings in 40 states and 21 countries, including testimony before the U.S. Congress and numerous state legislatures, the U.S. National Academy of Sciences, the President’s Council on Bioethics, European Parliament, British Parliament, Canadian Parliament, Australian Parliament, German Bundestag, French Senate, Swedish Parliament, the United Nations, and the Vatican. He was selected by President George W. Bush’s U.S. President’s Council on Bioethics to write the comprehensive review of adult stem cell research for the Council’s 2004 publication “Monitoring Stem Cell Research.” Dr. Prentice has published numerous scientific and bioethics articles, including a recent review of stem cell science and adult stem cell treatments published in Circulation Research. He has also published numerous commentaries and op-eds, and travels nationally and internationally to give frequent invited lectures regarding stem cell research, fetal tissue research, gene editing, cloning, embryology, cell culture and vaccines, bioethics, and public policy. He has been interviewed in virtually all major electronic and print media outlets, including CNN, ABC, NBC, CBS, Fox, CSPAN, Reuters, AP, NPR, USA Today, BBC, The Washington Post, The Los Angeles Times, and The New York Times.

3 Comments

  1. Dr. David Greene on February 12, 2020 at 2:22 am

    Stem cells are far more effective and safe and useful, we will ever find. In the last few years, individuals have turned to these treatments rapidly by abandoning painful surgeries.



  2. Dr. David Greene on February 27, 2020 at 2:22 am

    Adult stem cells have been delivering tremendous results from years and individuals have got rid of painful surgeries.



  3. Machigahan Scholarship on June 14, 2022 at 5:27 am

    Thank you for the informative article. It was, in reality, a humorous tale. Look forward to hearing from you in the near future! Thank you.